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The MemBrain also employs a powerful machine learning technique, the optimized evidence-theoretic K-nearest neighbor (OET-KNN) algorithm, which will output a propensity of residue belonging to TMH segments.
Such capability was realized by applying the powerful optimized evidence-theoretic K-nearest neighbor (OET-KNN) prediction algorithm [12] [14] to protein sequence representations that include sequence evolution information, and by merging results from prediction sequence windows of different sizes.
The prediction engine used in this study is the ensemble classifier
To improve the accuracy of TMH detection, we developed a machine-learning based predictor, MemBrain, which integrates a number of modern bioinformatics approaches including sequence representation by multiple sequence alignment matrix, the optimized evidence-theoretic K-nearest neighbor prediction algorithm, fusion of multiple prediction window sizes, and classification by dynamic threshold.
Although the new design is not optimized, experimental evidence shows that it can significantly reduce cracking near a sleeve split.
The hemodynamics of our patients were in part optimized, as evidenced by ScvO2 values above 70% in both groups.
Patient care can be optimized via evidence-based, yet locally developed and reiterative standardized clinical assessment and management plans for patients with coronary artery stents undergoing surgical procedures.
Patient care can be optimized via evidence-based, yet locally developed and reiterative SCAMPs for patients with coronary artery stents undergoing surgical procedures.
The fast-track set-up was implemented in 2003 and consists of optimized logistics and evidence-based clinical features (as described in detail below) (Husted et al. 2008).
This is to be expected, as fast-track surgery consists of a combination of optimized logistics and evidence-based clinical features, thereby providing the best-documented treatment available the "right track" (Kehlet and Søballe 2010).
24 patients operated with bilateral simultaneous (sequential) total knee arthroplasty (TKA) were included in this randomized, double-blind, placebo-controlled study, in a fast-track setup where we concentrated on optimized logistics and evidence-based clinical features (Husted et al. 2008).
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