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Optimized effects were achieved at 10 kGy, under the assayed dose range, with regard to higher particle size and protein crosslinking levels.
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We find that the nanoparticle sizes that have been reported to produce the optimized effect on cancer cells are of minimum absorption bandwidth and optimized electric field magnitude.
Reaction conditions are optimized, effect of functional groups on performance of the catalysts is taken into consideration and reusability of the designed heterogeneous systems is studied.
Unfortunately, the scientific basis for the design of such techniques does not exist in some cases or not appropriate enough in order to have an optimized effect.
To interrogate the intervening mechanism(s) and the conditions responsible for the optimized effect, not only just the experimental observations but also a sound theoretical model would be necessary for analysis.
Our model provides different parameters for the direct identification of the NPs' size for optimized effect on cancer (absorption band width); the other model considers the intensity and distance to which the electric field would extend from the nanoparticles surface.
The turning point is found to coincide with the median value for the size range (10 30 nm) and it corresponds to the Au NPs' size reported to show the optimized effect on cancer cells.
This could suggest that the metal NPs showing optimized effect on cancer cells and dye/solar cells, in all shapes, may be related and the shape transformation may only be to improve other aspects.
2D CFD simulations was carried out to verify the optimized effect of VRGV out of nine different angles of roof designs and to estimate the increased speed by the VRGV.
According to the model, the variation of the absorption bandwidth with the NPs' size exhibits a minimum turning point around the NPs' sizes that have optimized effect on both the electric field enhancement and the EMF effect on the cancer cells.
The results indicate that it took about a generation time (4-hours) in M. smegmatis for observing the optimized effect of the IPTG induction.
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CEO of Professional Science Editing for Scientists @ prosciediting.com