Sentence examples for optimized derivatives from inspiring English sources

Using computational methods, we have derived two optimized derivatives of trans-cyclooctene, which pave the road to more efficient in vivo labeling of arbitrary proteins.

Optimized derivatives display high selectivity over IP, FP, and other EP receptor panels.

A mechanistic model of uncoupling of oxidative phosphorylation by lipophilic weak acids (i.e. proton shuttles) was developed for the purposes of predicting the relative activity of xenobiotics of widely varying structure and of guiding the design of optimized derivatives.

The model was used to tentatively identify several novel proton shuttles, as well as to elucidate core structures particularly conducive to proton shuttle activity from which optimized derivatives can be designed.

Martins et al. [35] conjugated an optimized derivative of the Pittsburg compound-B (PiB), a well-established marker of Aβ plaques, to DO3A-monoamide, which is capable of forming stable, non-charged complexes with Gd (and other trivalent metal ions).

Doyle et al. (2006b) developed bioluminescent C. albicans using a codon optimized derivative of the firefly luciferase gene.

Thus, the optimized derivative, AptAF42d1, blocked cytokine GRO-α production induced by IL-17A/F, but not by IL-17A/A or IL-17F/F, in human cells (Fig. 5C).

The antigen surrogate, or more likely an optimized derivative, could be employed as a "capture agent" in ELISA-like assays of potential diagnostic utility.

PRIMA-1 and its optimized derivative PRIMA-1MET are proved to specifically inhibit p53 mutant tumor growth by restoring the function of mutant p53.

By using non-equispaced grid points near boundaries, we derive boundary optimized first derivative finite difference operators, of orders up to twelve.

It is shown that optimized spatial derivatives perform poorly for waves that are not of constant amplitude, under performing maximal-order schemes.