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We can use these optimized constraints to not only infer structural characteristics of the regulatory complex, but also to quantify the binding of these multi-meric complexes to different DNA sequences, and to accurately predict target genes.
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Thus, the necessity of formulating the design of a nuclear reactor core as an optimization problem, where the decision variables are optimized taking constraints into account.
Obtaining a correct Pareto front is not a trivial question, because it depends on the complexity of the objective functions to be optimized, the constraints to keep within and, in particular, the optimizer type selected to carry out the calculations.
Our method was optimized using constraints for smoothness, discontinuity, and sparsity, when we only have data of insufficient quality.
This objective function is optimized considering constraints for the maximum number of meters that can be installed and for the accuracy of the state estimator.
In the first one the robustness margin is maximized for a given lower bound on the crossover frequency, whereas in the second one the closed-loop performance in terms of the load disturbance rejection is optimized with constraints on the new stability margin.
The VAT method would seem the most straightforward to utilize in most field situations, and under optimized sampling constraints the method holds promise for row crops [ 14].
Results show that the element density distribution of the strut model was optimized with manufacturing constraints of extrusion constraint and minimum member size control.
We apply this technique to a model problem involving a vibrating system whose resonant frequency or whose spectral gap is to be optimized subject to constraints on geometry.
Then, the intensity distributions within the treatment fields were optimized to gratify constraints of different normal tissues and targets like mentioned above.
The geometry of the two-layer ONIOM model was fully optimized (without any constraint).
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