It was next optimized by fitting it simultaneously and experiment-specific to data of PDE inhibition experiments (Additional file 1, Part II, Section 3), AC stimulation experiments (Additional file 1, Part II, Section 4) as well as to phosphorylation data of VASP phosphosites (Additional file 1, Part II, Section 5, 6).
The throughput of the selected route is further optimized by reconfiguring it in the position-aware optimization phase.
The prevailing model at work in staffing marketplaces needs to be optimized by, say, making it easier for employers (or clients) to connect with their regular and most trusted freelancers — or by giving freelancers the potential to, over time, be able to turn hourly gigs into full-time gigs (and incentivize clients to hire their favorite freelancers).
After it, a specific measure of efficiency has to be defined to simulate the new optimized consumption provided by it, through the modification of appropriate input parameters (e.g. reduction of door opening time (tdoor or P) to decrease warm air infiltration, or rise of internal temperature (Tint) up to a value near to the one that is recommended for product's preservation).
However, DI was not sufficiently optimized because it was selected by phage display from a 12-mer random library (4.1×1015 possible members) with a size of ∼108 that did not cover all of the possible sequences.
This class of problems associated with precedence constraint has been previously modeled and optimized by the authors, in which, it requires a multidimensional optimization at the same time: what to make, how many to make, where to make and the order to make.
In Section 6, we derive PID control [58] optimized by genetic optimization algorithm [59 61].
Both systems are optimized by an iterative optimization procedure.
For instance, it allows for execution schemes to be optimized by choosing effective rollback schemes.
Replacing an uniform profile by an optimized profile, it is possible with the same number of molecules to increase the absorption at low intensity from a factor 1.9, while transmission at high intensity remains near to 100%.
One vector is optimized by chemical names, and the other is optimized by non-chemical names.
