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In this study, three appropriate cellulase reagents were selected by multivariate analysis technique and then optimized by design of experiments method for efficient hydrolysis of alkali-pretreated rice straw.
The LC conditions were optimized by design of experiments (DOE) to obtain optimal separation in the shortest possible run time.
The analytical conditions were optimized by Design of Experiment (DoE) techniques (an exploratory Plackett Burman design followed by a factorial design on three selected variables).
The maximum dissolution rate was observed when Soluplus® and HPMCAS-HF was in ratio of (60 20) as optimized by design of experiments study.
The instrumental conditions were obtained and optimized by Design of Experiments (DOE – factorial and response surface model), having as factors: separation voltage, ionic strength (buffer concentration), pH and temperature.
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The synchronization criteria are further optimized by optimally designing a quadratic Lyapunov function to more precisely estimate the synchronization error bound.
Factors affecting hydrolysis were screened out by Placket Burman design (PBD) and most significant factors were further optimized by Box Behnken design (BBD).
The SPE procedure was optimized by factorial design, using ATZ as a model substrate.
Media components were optimized by statistical design for cell growth and PHB production of Methylobacterium extorquens DSMZ 1340.
The experimental conditions of temperature, amount of catalyst and ethanol:oleic acid molar ratio were optimized by using design of experiments (DOE) and canonical analysis.
The activity of purified keratinase with respect to pH, temperature and salt concentration was optimized by Box Behnken design experiment.
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