Sentence examples for optimized affinity to from inspiring English sources

We optimized affinity to Hsp90, in vitro cell growth inhibitory activity, water solubility, and liver microsomal stability of inhibitors and identified CH5138303.

There, thiols are categorized as 'soft' so an appropriate metal substrate being also soft should lead to optimized affinity.

MultiGraft Interface can be generally applied to engineer novel binding partners with altered specificity and optimized affinity.

We used yeast surface display to engineer an EETI-II-based knottin peptide that contains an 11-amino acid sequence in place of Loop 1, and a 10-amino sequence in place of Loop 3. As a model system, each engineered loop contained a separate Arg-Gly-Asp (RGD) integrin-binding motif [25], whose flanking residues were optimized to bind with high affinity to tumor-associated integrin receptors.

Hemagglutination inhibition assay showed that these synthetic glycoproteins have higher affinity to HA than the small clusters of sialosides with lower valency, due to multivalent effect and optimized three dimensional presentation of sialosides on the protein platform.

I felt such an affinity to him".

ligand affinity to target protein.

Solution: Screen for affinity to mission.

Bisphosphonates possess strong affinity to bone.

Affinity to the purpose is created by the affinity to the environment.

"We do have an affinity to land.