Your English writing platform
Discover LudwigExact(9)
As viral TEVp is expressed in plants, a codon-optimized (human) sequence was synthesized (GenBank accession # DQ516974) by a commercial source to optimize translation efficiency in mammalian cells.
Development of future tools should address these issues to optimize translation of knowledge into clinical practice.
These tools offer the opportunity to evaluate multiple hypotheses and provide a means to identify, quantify, and understand relevant sources of variability, to optimize translation and clinical trial design.
For example, a codon whose frequency is positively associated with expression level may be under selection to optimize translation efficiency and/or accuracy.
Some of these changes could reflect mutational biases that were revealed after the release of the pressure to bias codon composition to optimize translation proficiency.
Relative to wild-type GFP, the EGFP protein contains a threonine at position 65 instead of serine and has an additional GTG (Val) codon after the initiating ATG (Met) codon to optimize translation initiation in eukaryotes.
Similar(51)
For example, Tuller et al. (2010) demonstrated that the proximal coding regions of genes from diverse species are rich in nonpreferred synonymous codons, probably reflecting an adaptive feature that ensures optimal ribosome density along the transcript and optimizes translation speed by minimizing the risk of collisions between ribosomes.
is a multi-departmental, multidisciplinary research center aimed at optimizing translation of advances in basic immunology from the laboratory to the clinic, understanding immunological diseases and events in humans and optimizing transfer of information and methodologies to achieve synergy between different disciplines of applied immunology.
We make a distinction between decoding accuracy (optimizing the codon reading and avoiding errors) and decoding efficacy (optimizing translation rates).
In the translation related model, one postulate is that there is a co-adaptation of synonymous codon usage and tRNA abundance to optimize translational efficiency.
These differences between TW and OW may have to be taken into account in future designs of strategies to optimize the translation of treadmill gait training outcomes into real life over-ground walking.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com