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A structure activity relationship was developed in order to optimize their potency and selectivity.
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A series of lipidated vancomycin analogues 1 bearing disulfide bonds within their lipid chains was designed and synthesized to optimize their ADME profiles while retaining antibacterial potency.
Such experimental flexibility will facilitate the study of factors that affect the potency, distribution and metabolism of different FP-containing complexes in vivo in order to optimize their function as an accessory immunotherapeutic agents.
The Americans will happily optimize their way to gold.
Most manufacturers optimize their printers to work best with their own brand of ink and paper.
I just tell them to optimize their choices to be exposed to growth.
Families pull out all the stops to optimize their children's scores.
"That makes it altogether more imperative that they optimize their savings," he said.
To sell them off in pieces to other networks "would not optimize their value," the executive said.
So members will optimize their sub-systems and sub-optimize the system.
Most individual taxpayers also try to optimize their tax situation.
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