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There are several MR contrast agents for liver imaging that can optimize studies for every indication.
Designs that optimize studies using two-color arrays combined with a limited number of samples (e.g. loop design, [ 27]) were not considered.
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Every surgical procedure has unique clinical characteristics that must be considered to optimize study design and conduct.
The study populations must be pathophysiologically uniform to optimize study power and therefore strict exclusions criteria must be used.
To optimize study conditions, we limited inclusions to sedated, mechanically ventilated adult patients, who received only parenteral nutrition.
To optimize study designs with respect to a minimal number of patients required and minimal overall costs, the effect of increasing the number of readers should be considered.
To optimize study power, assessments of interaction were limited to dichotomous variables (SE-positive vs. SE-negative, ever vs. never smoking) and to two-way interactions.
Indoor air in five households without children was also sampled because residents were concerned and adamant about having their indoor air tested or because residents participated early in the study to help optimize study procedures.
The main objectives of PG are to cultivate collaboration, optimize study design, set-up and research activities of population-based biobanks, devise schemes to promote harmonisation of biobanks, and facilitate transfer of knowledge between group members and other interested parties.
To optimize study design and ascertain safety and efficacy of the chosen loading dose of 540,000 IU of cholecalciferol, we performed a pilot trial in 25 medical critically ill patients with vitamin D deficiency [ 25].
The need to appropriately adjust for population stratification in the presence of heterogeneity opposes the simultaneous need to optimize study power, a problem that remains highly challenging in the transethnic GWAS field.
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