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Taken together, this machinery is able to automatically optimize force fields and it is extensible by developers with regard to further optimization algorithms and simulation tools.
The question addressed here is how a phagocyte may use geometric cues to optimize force generation for the uptake of a particle.
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These issues should be examined in more detail, but suggest for example that optimizing force fields against structures from the PDB may introduce biases in the estimated parameters.
Taken together, this machinery is able to automatically modify and optimize the force field by way of user-selected potential functions for mesoscale polymer simulations.
While our current data do not allow us to definitively rule out this possibility, we consider it to be unlikely that postures were selected to optimize only force manipulability.
To optimize contractile force output of myobundles, myogenic cells were expanded in media containing either bFGF (Ham et al., 1988) or EGF (Cheng et al., 2014).
The mono-objective optimization results gave the combination of 40 m/min cutting speed, 0.10 mm/rev feed rate and 0.5 depth of cut when run under MQL for optimizing the tool wear and cutting temperature and also the same combination optimized cutting force when operated under dry condition.
The results from the simulation and the experiments have good correlation and show that wrinkling can be minimized by optimizing the force distribution around the edge of the manufacturing tool and by careful choice of forming temperature.
Optimized Atomic Force Microscopy (AFM) has indeed revealed the spatial inhomogeneity of viscoelasticity over a cell [ 44].
According to del Castillo and coworkers [ 1], larger filters allowed higher blood flows, optimizing shear forces and reducing protein layering, with consequently decreased membrane clotting.
Based on the improved exponential approach law, the algorithm of coordinating control is designed to optimize the traction force and minimize the slip ratio, including the velocity and normal force control and sliding mode control.
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