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As a first step in development of a computational tool for peak analysis, we used the newly found monoallelically expressed genes and Snrpn as a "learning tool" to optimize criteria for peak selection (Text S1).
Understanding of its molecular complexity is incomplete and there is a need to identify new therapeutic targets and to optimize criteria for its diagnosis, assessment and prognosis.
We emphasize that quasispecies estimation tools are designed for datasets of much higher coverage and diversity, and thus optimize criteria and utilize parameters specific to those applications.
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The objective is thereby to select, by optimizing criteria, the best path for conveying data to the destination.
GAs and PSO are both methods that optimize the optimization criterion using exploration and exploitation schemes.
So, since the initial release of the standard, several implementations were proposed, some targeting specific optimization goals whereas others would optimize several criteria while building the routing topology.
Furthermore, ant colony optimization outperforms the simple stepwise selection strategy since it can optimize several criteria simultaneously (model fit, reliability, and preset sex differences).
Optimize scheduling criteria and also provide load balancing.
Each technique defines a mathematical model that is used to optimize corresponding criteria.
The main objective of the modeling work is to better understand the process in CWs and optimize design criteria.
If the sources are assumed to be statistically independent, solutions to the BSS problem are calculated so as to optimize separation criteria based on higher order statistics[6, 7].
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