Sentence examples for optimize consensus from inspiring English sources

We used a custom assembly workflow to optimize consensus genome map assembly, resulting in an assembly equal to the estimated length of the Tribolium castaneum genome and with an N50 of more than 1 Mb.

These findings led us to hypothesize that in many cases, Cdk substrates might contain clusters of phosphorylation sites, and therefore that Cdk substrate prediction could be improved not only by optimizing the consensus motif sequence, but also by following consensus site identification with selection of proteins whose sequences are enriched for repeats of that motif.

In fact, Hapler optimizes the consensus sequence C via dynamic programming based on several criteria of decreasing importance: 1. Minimizing the number of possible crossover points in C. 2. Maximizing the total supporting read coverage (both redundant and irredundant) of alleles used at SNP positions in C. 3. Minimizing the number of unique haplotype assemblies used.

To optimize enfuvirtide use, consensus recommendations for this purpose have been formulated by 247 physicians attending patients with HIV infection in Spain.

In this study, we have optimized ODEC using consensus sequence design, cyclic permutation, and structure-guided mutations to generate a number of variants with improved yields, biophysical properties, stabilities, and affinities (KD of 10-50 nm) for various CD4bs targeting broadly neutralizing antibodies, including the germline-reverted version of the broadly neutralizing antibody VRC01.

Protein-DNA matrix complexes were washed with 150 µL binding buffer for 5 min on a nutating mixer at 4°C, followed by a wash with binding buffer containing 250 mM KCl and a third wash containing 500 mM KCl. Washing conditions were optimized with the consensus DBE, and 500 mM KCl was shown to be sufficient to remove most of the unspecific binding.

The modular design of these algorithms makes it possible to sequence their constituting steps in different manners, which allows to derive versions of the proposed consensus functions optimized from a computational standpoint.

Towards this end, we constructed MVAΔudg-gag and MVA-gag, which commonly express a synthetic, human codon-optimized, HIV subtype-B consensus gag gene from an early viral promoter at MVA deletion site-III and differ only in their udg genotype, and used these viruses to immunize two groups of rhesus macaques (N = 6/group) with 2×108 PFU of virus at 0, 6, and 12 weeks.

Holland and colleagues [ 42] further optimized their original greedy consensus network method to incorporate weights from individual trees into the network inference process.

Fitch optimization (reversible parsimony) [ 121] was performed in TNT to optimize the area on the strict consensus tree [ 125].

Therefore, we can minimize the energy consumption for consensus process by optimizing transmit power, network topology, and weights γ(j).