Sentence examples for optimization of the binding from inspiring English sources

We present a multi-objective optimization of the binding properties of a molecularly imprinted polymer (MIP) which specifically binds glucuronic acid (GA).

The working range was 5 320 nM with negligible possible interference from the different background composition of water samples by optimization of the binding conditions.

Contour maps and molecular docking identified that the R1 and R2 natures at the pyrazole moiety are the important features for the optimization of the binding affinity to the DHFR receptor.

Since at the initial stages of the double helix formation multiple weak interactions exist, the corporation must bring to the table attractive investments and a support system enabling optimization of the binding capacity during the double helix formation stage.

In our previous study, we have presented pose prediction and ranking results using pharmacophore models without any local optimization of the binding poses or use of an atomistic scoring function.

Optimization of the binding geometry was performed with RosettaDock with distance constraints.

For optimization of the radioligand binding assay, a standard mixture of NBI-74330 and VUF11211 (both at 20 μM concentrations) was separated using the LC conditions described above, and collected onto 96-well plates.

Optimization of the transcription factor binding tools revealed that both TESS and Matinspector, using default parameters, correctly predicted the previously described -1501, but not the -1569 estrogen receptor (ERE) motif in the Atlantic salmon GnRH-III upstream promoter (Pa) [ 34].

The optimization of lead compounds as viable drug candidates involves the optimization of their binding affinity towards the selected target.

Since these compounds pay a larger conformational entropy penalty upon binding, the optimization of their binding affinity requires the presence of a favorable binding enthalpy.

The design of experiment with response surface methodology and multiple optimization response was used to maximize the recovery of fluorescent probe at the end of the assay simultaneously with the optimization of target probe binding.