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Optimization of pH, reducing extract concentration, metal ion concentration and time elapsed from the nano-biosynthesis was achieved.
Further, Response Surface Methodology was used for optimization of pH, temperature, and sodium bicarbonate for higher biomass and PHB production.
The central composite design was further used for optimization of pH and benzene concentration to enhance the benzene biodegradation.
After the optimization of pH and salt addition, high IgG purity of 98.4% could be obtained with the recovery of 89.4% from BSA-containing feedstock.
The predicted results of 3-DMC yield (7689.13 mg/l) were obtained at 5-l-jar fermenter after optimization of pH 6.8, temperature 28°C, impeller tip velocity 4650 cm/min, and aeration rate 2.0 vvm.
Increase in lactic acid production (15.1 g/l) was observed with supplementation of salts and organic nitrogen sources of MRS medium and after optimization of pH and temperature using date juice as a C-source.
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Luo, M. et al. Construction and optimization of pH-sensitive nanoparticle delivery system containing PLGA and UCCs-2 for targeted treatment of Helicobacter pylori.
After optimization of immobilization pH, incubation pH and time, and blocking reagent, several immobilized biocatalysts on amino-vinylsulfone support having 50 80% of the initial activity and a stabilization factor of around 8 15 were prepared, depending on the exact immobilization conditions.
Erbas-Cakmak, S., Cakmak, F. P., Topel, S. D., Uyar, T. B. & Akkaya, E. U. Selective photosensitization through an AND logic response: optimization of the pH and glutathione response of activatable photosensitizers.
For the optimization of buffer pH and ionic liquid concentration a design of experiments approach was performed.
Optimization of formulation pH, as well as the EDTA and ethanol concentrations, allowed for the identification of formulations that further enhanced long-term storage stability.
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