One favourite was John and his crew on the documentary Life Begins Now, three adolescent boys with Down's syndrome, who were preparing to leave college for a life John optimistically considered would be full of guns, strippers and other thugged-out accoutrements.
Availability of and access to data are both technical and political challenges, although they are optimistically considered to be surmountable.
Most optimistically, he considers the entry of Wal-Mart into the market as validation of his business strategy, which he considers to be a combination of both old- and new-economy approaches that once might have been dismissed by 90's-era promoters of the "new new thing" as hopelessly old-fashioned.
I optimistically see the cup of leadership half full this year.
Parameters such as potential BE diagnosis-related reduction in quality of life or increase in health care use, diagnostic accuracy, and infrastructural costs (for quality assurance) were considered either "optimistically" or not at all.
Considering the rapid progress made in the past 15 years, we can optimistically expect that many of these questions will be answered by the next edition of the YeastBook.
Considering the current system's rate of return, the DJI equivalent would be, very optimistically, around 20,000.
Much has yet to be discovered with regard to safety profiles and improved manufacture yet considering how carefully derived rational insights might be combined with computational biology to accelerate complex performance models, prospects that graphene-based biomaterials can achieve extraordinary real-world benefits are optimistically poised.
The authors optimistically attributed many of the patient's symptoms including the speech delay to the disruption of FOXP1, but the contribution of PROK2 and GPR27 to the phenotype cannot be ruled out, especially considering that both genes were previously implicated in developmental retardation (Petek et al. 2003).
It is obvious that in these three extreme cases of Limburg, Aubervilliers and Rotterdam the main effort is to break with uniform machinery by introducing diversity, adopting a somewhat conformist way which optimistically prefers those solutions generally considered today the most innovative and intelligent: ecology, technology, media and waste management.
