Exact(1)
The capacity to orientate the enzymes either towards or away from the interface (phase boundary) and the ability to manipulate the radial location of component proteins when immobilising two or more proteins could also allow for optimising activity, especially for large substrates.
Similar(59)
As part of a research effort to improve the quality of current chemotherapy of Pneumocystis carinii pneumonia, we report a structure-based design project to optimise activity, species selectivity and pharmaceutical properties of the triazenyl-pyrimethamine TAB (4) (IC50=0.17 μM; rat liver DHFR IC50/P. carinii DHFR IC50=114).
Therefore, a systematic structure activity relationship (SAR) analysis of BTCP (1) was undertaken to optimise activity against both TryR and the intact parasite T. brucei.
This is not always easy to conclude, but it is essential to optimise activities and maximise the project's success.
Like Delgado, these teams will be responsible for delivering on day-to-day campaigns, optimising marketing activity and producing outstanding creative.
Shopping comparison websites, such as Kelkoo, Pricerunner and Shopping.com, also provide a good place to start with performance marketing but as these sites tend to charge for traffic, you need to be careful you optimise your activity with them accordingly.
Knowing how specificity is controlled, would allow to optimise this activity in an efficient way by means of enzyme engineering.
This buffering capacity makes peat an attractive medium for engineered biological systems which must often operate within narrow pH bands to optimise biological activity.
The challenges involved in using rational (3D QSAR-based) drug design to optimise the activity profile of analogues of 2MEO to provide additional members of this new class of anti-tumour/anti-inflammatory drug are also outlined.
Rather, it is suggested that a market driven approach is required to ensure optimal performance of the recycling system in which each actor in the system optimises its activity within the boundaries of its relevant environmental legislation, physics, chemistry, which all dictate the limits of recycling.
15 Alcohol is frequently combined with CHG or iodophors to optimise the activity of the surgical skin antisepsis.
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