Sentence examples for optimised the target from inspiring English sources
Once the MS were optimised, the target loading of rhEGF was increased to 1% (PLGA-Alginate MS), and particles were sterilised by gamma radiation to provide the correct dosage for in vivo studies.
However, the current levels of structural safety are not necessarily the most appropriate, and it has been suggested that explicit risk-based measures of structural performance should be used to optimise the target levels of design performance.
In an effort to optimise the targeting and therapeutic efficacy of ALM, we hypothesise that strategies to alter the affinity for either one or both of the arms for their target antigens can be used to increase the window of selective targeting achievable with bs-scFvs targeting ErbB2'+'/ErbB3'+' tumours although not impairing the overall tumour retention.
Based on the very good benchmarking results, this code is now used to design and optimise the new target and to assess all relevant parameters influencing the neutron flux and resolution functions.
E.K.D. optimised the conditions for the co-culture system.
WJ optimised the inverse PCR assay.
VW designed and optimised the screening assay.
Therefore, there is a need to perform model identification at both qualitative and quantitative levels, that is, qualitatively explore the model structure space (the topology of a model) and quantitatively optimise the parameters of the target biochemical systems in an integrative manner.
The study shows that laboratory scale pre-investigations can help with tracer selection and to optimise the concentration range targeted for in situ multilevel monitoring by unspecific geoelectrical instrumentation.
Instead of exploring dose recommendations by simulation, we aimed to optimise the dose based on the target SDS and we minimised deviations from this using least-squares regression.
Experimental results indicate that our proposed integrative framework is feasible to learn the relationships between biochemical reactants qualitatively and to make the model replicate the behaviours of the target system by optimising the kinetic rates quantitatively.
