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In order to optimise sample size in the present study we performed meta-analysis of GWAS using a number of cohorts having the LDD phenotype.
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It allows study design to be optimised by enabling an appropriate sample size calculation to be made, and ensures that the resulting data will be suitable for the most appropriate statistical analysis.
To optimise safety and efficacy information, the sample size was set to 42 patients per arm.
To optimise imaging quality the samples were processed, reducing sample size and approaching original tooth size.
There are design challenges relating to this trial and a multi-stage approach has been utilised to optimise the effectiveness of the design in terms of time and sample size.
Statistical power in epidemiological studies is optimised by classifying birth defects into aetiologically homogeneous groups and expanding the sample size of the monitored population.
The sensitivity of karyometric detection can help optimise the design of clinical trials of novel chemopreventive agents by decreasing trial duration and/or sample size.
Following the framework and its elements for optimising trial parameters [ 27], the trial analysis will also provide data for calculating sample size and the effect size estimate for a future definitive trial.
Sample size and no sample size.
It could be sample size.
Small Sample Size Theater ladies and gentlemen!
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