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Correct determination of doses to and dose-distributions within patients at different levels of spatial resolution is necessary depending on the required purpose in terms of radiobiological questions or optimisation of procedures.
Although it would be quite difficult to calculate the real benefit of the use of such measures on the quality of our principal outcome, the final diagnosis, radiologists must pay attention to this topic by choosing a non-ionising examination technique whenever possible and the optimisation of procedures.
Note that doses may have been reduced since the early 2000s, thanks to technological advances in CT and better optimisation of procedures.
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Solid-phase microextraction was also valuable for detection of residual VOCs in the breath sampling device that resulted in optimisation of cleaning procedures.
Theory and methodology of a central composite design as a chemometric method for the optimisation of analytical procedures were developed in this approach.
The factor represents the efficiency gains that will be achieved in the air transport system by e.g. optimisation of operational procedures, air traffic control or the introduction of larger, more modern and more fuel-efficient aircraft.
This follows the guidelines contained in the European Directive 2013/59/EURATOM issued on 5 December 2013 [4], which gives challenging targets to all stakeholders in terms of justification and optimisation of the procedures using ionising radiation.
The promotion of the optimisation of CT procedures and the use, as often as possible, of non-irradiating techniques such as magnetic resonance imaging must continue, especially in paediatrics.
Optimisation of DLLME procedure was performed by evaluating the type of disperser and extraction solvents and the temperature and salt addition effects.
Optimisation of administration procedure in combination with adjustment of frame times of the dynamic scans might improve the performance of the tested KF methods.
Optimisation of the procedure for detection and separation of benzothiazole-DNA adducts preceded in vitro studies to investigate time- and dose-dependent accumulation of 5F 203-DNA adducts in MCF-7 mammary carcinoma cells.
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