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Not surprisingly, there is a perpetual arms race (euphemistically called search engine optimisation) between Google and people attempting to game PageRank.
The optimisation between performance and safety involved a large investment on design criteria.
Safety climate may afford a means for assessing the degree of joint optimisation between organisational and technical sub-systems.
This indicates that an increase of genetic diversity in the current population can be achieved by optimisation between clusters but not by breeding within clusters.
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Another difficulty is the necessity, in some cases, of a global optimization between ascent and re-entry phases (branching optimisation).
It is intended to establish a new order optimisation principle between the interlaced planning levels, which allows an improved real-time decision making.
For each value of RR from 16 to 48 b/min at each step, the corresponding values of V T (denoted by p 1, p 2,…, p 5) are selected by an optimisation algorithm between a lower bound of 2.5 ml/kg and an upper bound of 8 ml/kg.
We excluded RCTs with no description of or no difference in optimisation strategies between groups, as well as RCTs in which therapy was titrated to the same goal in both groups or was not titrated to predefined end points.
In this article, we have also reviewed the theories on which IPE is based and its suitability for application to the discipline of geriatric medicine (e.g. regarding curriculum design, clinical practice, and the optimisation of collaboration between team members).
In research Drożdziel et al. [7] make a proposal of solving the problems within the East – West transport by building a new broad gauge infrastructure, but they did not make any analyses for organisational optimisation in transport between the East and West.
However, the optimisation of linkers between the binding groups can be challenging, and, yet, is crucial in both fragment-based ligand (and drug) design and in the discovery of bisubstrate inhibitors.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com