We finally developed the deck house shape of high-speed planing crafts that optimally decreased air resistance.
Table 2 Summaries of reviewed systems approaches for identifying drug combinations Disease models Method Key findings Validation Reference Computational models of cell signaling networks Breast cancer Mass-action model Combined inhibition of MEK and PI3K optimally decreased cell viability.
In preliminary dose response experiments, we found that 150 nM STS for 24 h optimally decreased viability measured by a live-cell protease activity assay (Supplementary Figure 2A) and increased lactate dehydrogenase (LDH) release (Supplementary Figure 2B).
The existence of community pressure may increase or decrease the optimal calibration of a formal intervention (in this case an environmental tax) and may complement or detract from the incentives generated by an optimally calibrated tax.
Moreover, poor performance status may prevent the use of optimally aggressive chemo- and radiation therapy regimens and/or decrease the ability to achieve radical surgical resection, thereby shortening long-term survival.
To improve robot performance for agricultural tasks, and decrease its cost, the robot can be optimally designed for a specific task in a specific working environment.
When used optimally, vaccines prevent disease manifestations, reduce transmission of disease, decrease the need for pharmaceutical intervention, and improve the health and welfare of animals, as well as indirectly protecting against zoonotic diseases of people.
According to this model, stroke rates and associated costs could decrease dramatically if 50% of warfarin-eligible patients were optimally coagulated.
If any these conditions are violated, sum-scores no longer optimally represent the latent trait, and the use of sum-scores may decrease the power to detect genetic variants for that trait, compared to more advanced phenotypic models, such as latent factor models.
The delay of these interconnects can be significantly decreased by optimally placing the interplane vias.
