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Internalization, routing to lysosomal compartments, antigen presentation and cytokine response could be optimally achieved with glycopeptide dendrimers carrying 16 32 glycan units.
The induction of Major Histocompatibility Complex (MHC) class I restricted CTL activity is optimally achieved by synthesis of antigens within APCs, for example, after immunisation with live attenuated virus.
Our methodology has two distinctive features, namely, a formal specification of use cases and a rigorous and systematic process for deriving a system design whose correctness and consistency can be optimally achieved.
The results of this work will allow making decisions about the flight plan and having enough confidence in those decisions so that the mission objectives can be optimally achieved.
Our findings highlight the possibility that therapeutic manipulation of NKT cells to improve immune responses against autoimmune or infectious diseases may be most optimally achieved by targeting specific subsets rather than the entire NKT cell pool.
Since advocacy is optimally achieved through strong partnerships, the latter is considered vital for promoting and enhancing the adoption of gender sensitive education programmes.
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Discussion Our protocol cannot optimally achieve target levels on days 1 2.
We hypothesize that detection and individuation require separate sets of facial features to optimally achieve their goals and that the visual system adopts this separation to perform different aspects of face recognition more effectively.
In contrast, in synergy, there is no prioritization of interventions during implementation; rather, emphasizing the mix of interventions to optimally achieve simultaneous multiple benefits while maintaining and enhancing system functionality.
Implantable middle ear hearing aid transducers, i.e. the equivalent to the loudspeaker in conventional hearing aids, should ideally fit into the majority of adult middle ears and should utilize the limited space optimally to achieve sufficiently high maximal output levels.
First, the problem is solved using formal hierarchical Bayesian modeling [25], and the knowledge transfer is achieved optimally, i.e. in the minimum-KLD sense.
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