Finally, other SF2 helicases have evolved to optimally accommodate dsRNA (e.g., RIG-I) or dsDNA (e.g., Sulfolobus solfataricus Swi2/Snf2) in a closed state complex and translocate with no observable unwinding (Durr et al., 2005; Myong et al., 2009; Jiang et al., 2011).
The empirical analysis shows how the model rationalizes the oil market in the period preceding the price collapse as a high-price accommodate scenario; OPEC optimally chose not to squeeze US shale despite having sufficient spare capacity to do so.
In addition, MS-MPC can incorporate, naturally, richer descriptions of external disturbances and model uncertainties over several distinct temporal scales (ranges of frequencies) and can accommodate, naturally and optimally, measurements at multiple sampling intervals and control actions at multiple rates.
In trying to accommodate these individuals as optimally as possible, it is important that they are provided with suitable housing conditions, which aim to minimise exposure to stress in order to maximise welfare.
It was hypothesized that breaking the Asn170 Asp240 hydrogen bond widens the active site to accommodate and position cefotaxime more optimally for catalysis.
The design concept included spawning of these templates to function as effective ligands to the catalytic zinc within the enzyme through incorporation of optimally substituted piperazino-triazine side chains so as to accommodate the active site in the enzyme for efficient binding.
The distinct spatiotemporal expression patterns of USP4 and USP15 could explain why these redundant proteins have been maintained: vertebrate genomes could optimally encode two versions of an ancestral protein to accommodate its important roles in germ and somatic cells.
Optimally, Mr. Shapiro said, floor sizes should be no more than 40,000 square feet to accommodate a variety of tenant needs -- about the floor size that architects have specified for Sutton Park South.
RosettaDock uses a low resolution Monte Carlo search and backbone optimization algorithm to optimally position a submitted monomer pair, followed by a refinement to relax the backbone and accommodate the side chains (Gray et al. 2003).
The BOMBARDIER INNOVIA Monorail 300 System can accommodate grades of up to 6%% and curve radii of 46-m radius permitting the guideway alignment to optimally follow existing rights of way (Fig. 20).
The rooted rings that optimally explain the distribution of both the genes and indels, shown in figure 3, are slightly more complex as they accommodate an additional indel in the GGGPS gene that is present in the Eocyta and is absent in the Halo bacteria.
