Exact(7)
This report also confirms that pantoprazole is a well tolerated treatment even for long-term therapy with optimal tolerability.
In this study canakinumab confirmed optimal tolerability together with a good safety profile [ 15, 16].
Therefore, an NVP-AUY922 intermittent dosing regimen gives optimal tolerability without significantly affecting efficacy.
All treatments demonstrated optimal tolerability and are suitable for frequent use in the therapy of dry eye.
In this study comparing TSP with HA, all preparations demonstrated optimal tolerability, with no reported onset of blurred vision, ocular redness, ocular burning or ocular itching.
Enriched enrollment, a treatment run-in after screening to titrate patients up to optimal tolerability, is frequently used in opioid trials due to their well-known dosing requirements.
Similar(53)
However, drawbacks such as sub-optimal tolerability and migration may affect both patient management and costs.
For instance, we may combine naproxen with eletriptan to attain treatments with both optimal efficacy and tolerability.
The major limitation is irritation and dryness from higher concentrations of benzoyl peroxide, and a combination providing optimal efficacy and tolerability has yet to be determined.
Despite the various combinations of clindamycin and BP available, the concentration of BP for optimal efficacy and tolerability is still unknown.
LDX treatment was initiated at 30 mg/d and, based on clinical judgment, could be increased or decreased in 20-mg increments at subsequent visits to achieve optimal efficacy and tolerability over a 4-week titration period.
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