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Voltaire's target throughout "Candide" is not optimism in the sense of fatuous cheerfulness but optimism in the sense of optimal thinking: the kind of bland reassurance that explains pain with reference to a larger plan or history.
But almost all of us still do believe, stubbornly, in some kind of optimal thinking.
Good nutrition is vital for optimal thinking.
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BUTLER: Just as exercise keeps the body in optimal shape, exercise — both physical and mental — can keep the brain in optimal shape in terms of thinking clearly, making judgments and solving problems.
"As a night owl, my own optimal time for writing or thinking creatively is from about 10pm to 2am.
We were thinking about the optimal solution to create effective stickers.
"Going back to the Google Express," Gurley went on, "I have a hard time thinking it's optimal for [Proctor & Gamble] to sell to Walgreen's distribution center, where [its goods are] offloaded, [after which] a guy with a box cutter puts it on a shelf, all to have some employee from another company take it off the shelf and take it to your house".
Said Gurley of the model that Instacart and select other startups employ: "I have a hard time thinking it's optimal for [Proctor & Gamble] to sell to a Walgreen's distribution center, where [its goods are] offloaded, [after which] a guy with a box cutter puts it on a shelf, all to have some employee from another company take it off the shelf and take it to your house".
Our experience with the intricacies of dealing with two control groups may be useful to others when thinking about an optimal research design or the best statistical approach.
See related research article In the past 5 years there has been a substantial shift in thinking regarding the optimal therapy of patients with severe community-acquired pneumonia (CAP), particularly with respect to pneumococcal disease.
But sooner or later, companies such as Optimal will surely have to start thinking about fresh machinery.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com