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Based on the complementary results obtained from immunization with non-lipidated rP6 in WT mice and native P6 immunization in TLR2−/− mice, we reasoned that optimal stimulation with P6 required the direct conjugation of the lipid motif to the antigen.
To measure the influence of activated B cells on CD4+FoxP3+ T-cell differentiation, CD154-L cells were co-cultured with sorted CD4+CD25− T cells and B cells at a ratio of 1 10 10 (CD154-L cells: B cells: effector T cells) in the presence of optimal stimulation with anti-CD3/CD28-coated beads at a ratio of 1 320 (beads: T cells).
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Finally, we provide some guidelines for optimal stimulation of carbonates with in situ cross-linked acids.
However, customers with different optimal stimulation levels did not show a difference in satiation patterns after repeated dining experiences.
Finally, the TRFH and Myb/SANT domains were required for optimal stimulation of a reaction associated with t-loop formation.
The theory of optimal stimulation suggests that hyperactive children with high stimulation thresholds exhibit stimulation-seeking behaviors in situations with low amounts of stimulation.
Interestingly, Pfa1 can stimulate ATPase activity with and without RNA, but optimal stimulation occurs in presence of RNA [ 53].
Dectin-1 can induce cytokine production independently of other receptors, as well as synergize with TLRs for an optimal stimulation of the cell.
In order to obtain optimal stimulation intensity, we determined participants' individual resting motor threshold (RMT).
The recordings are performed by immobilizing and mounting larvae for optimal stimulation of lateral-line hair cells.
It's also to seek for optimal stimulation parameters (intensity, frequency, number and duration of stimulation sessions).
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