Sentence examples for optimal specificity from inspiring English sources

Each oligonucleotide was designed with an optimal specificity and sensitivity to its target gene and has an optimized Tm value.

Visual non-stress test interpretation lacks the optimal specificity and observer-agreement of an ideal screening tool for intrauterine fetal demise (IUFD) syndrome prevention.

The substrate requirement of the native enzyme has an optimal specificity for zymosterol with associated kinetic constants of Km 50 μM and kcat of 0.01 s−1.

Secondary pharmacology is an essential component of drug discovery and is used extensively in the pharmaceutical industry for achieving optimal specificity of new drugs via early hazard identification and off-target mitigation.

At cut-offs set for optimal specificity of 90% or more, the sensitivity of each gene in PT was over 70%.

Receiver operating characteristic (ROC) curve analyses indicated that cut-off values for CD28% = 82 seemed to provide the best compromise of optimal specificity (the most important consideration) and sensitivity for these major, adverse clinical events.

For example, the optimal specificities of kinases [ 81– 83] and SRC Homology 2 (SH2) domains [ 84, 85] have diversified during family expansions.

In our analyses, we chose to set individual scoring thresholds for each gene based on the highest PMR value achieved among the normal mucosa samples in the test set to ensure optimal specificities.

Although IP-10, like ADA, has sub-optimal specificity, it may be a clinically useful rule-out test for tuberculous pleural effusions.

The sub-optimal specificity observed represents positive assays occurring in 3 subjects with a final diagnosis of quiescent or latent TB.

Although IP-10 levels were significantly higher in TB compared to non-TB patients it was not clinically useful because of the sub-optimal specificity in the non-TB group.