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The response optimizer was employed to generate the optimal set of four factors leading to the desired criteria of response variable.
The above procedure was repeated to produce an optimal set of eight genes, this time starting from the top 90 non-redundant probe sets (excluding the 10 genes with problems identified above), k-means clustering (k = 8) these genes and selecting the best gene from each cluster (Additional file 1: Figure S2).
The identified evidence was quiet strong that building haploblocks using a D′≥0.45 threshold produced an optimal set of variables for all three traits tested.
By combining the optimal setting of these two influential processing variables, a fine powder with a particle size of ≈2200 Å was obtained.
Table 6 shows that the pathway and pathway pair classifiers constructed from the genes selected via IFR have discriminative power comparable to the optimal set of genes selected by SSVM, over four data sets.
For fifteen locations, the optimal set of technologies, their capacity and operation was identified.
In Table 2 we report the optimal set of probabilities for the collaboration networks from the two different domains.
In part, the cause of the strong correlation between end of exon usage in Drosophila and mammals reflects the fact that the "splicing optimal" set of codons and the "translationally optimal" set of codons are two almost mutually exclusive sets of codons, that is, translationally optimal codons tend to be those avoided near exon boundaries (Warnecke and Hurst 2007).
Still, using a Silicon Graphics Origin 2000 supercomputer with 32 processors it took more than two weeks of continuous operation to find an optimal set of parameters.
The trade-off among three objectives can help to identify most beneficial solution from Pareto optimal set of solutions.
There is no "optimal" set of tools.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com