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Pure LPFGs show the optimal sensitivity to 55 60% of sucrose solutions.
LPFGs assembled with 100 bilayers of PAH/PSS exhibited the optimal sensitivity to 20 25% of sucrose solutions.
The concentration of t-PA used for the assay has been adjusted (100 ng/ml) to obtain an optimal sensitivity to hypofibrinolysis within a short time interval, and clot dissolution occurs within about 45 min for normal individuals, with a broad range from 30 min to 60 min, with some samples presenting a clot dissolution time >60 min (hypofibrinolysis).
If however the solution realized in nature is such that Δm2sol≳2×10−4 eV2 (thereafter named the HLMA region), KamLAND will only observe a rate suppression but no spectral distortion and hence it will not have the optimal sensitivity to measure the mixing parameters.
The signature thresholds were based on an optimal sensitivity to correctly identify all known oncogenic mutation carriers and all other samples that harboured the activating oncogenic signatures.
The vibrotactile frequency was set to the range from 170 to 185 Hz as an optimal sensitivity to tactile vibrations is achieved at frequencies between 150 and 300 Hz (Jones & Sarter, 2008).
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To guarantee optimal sensitivity, filters to select variants that affect exonic sequence (Gene Location filter) or lead to a premature stop codon (VariantType filter) are applied in a transcript-specific manner.
Since optimal sensitivity leads to a sensitivity that is infinite, we truncated fraction hits and false alarms at.99, leading to a maximum d' of 4.7.
Cutoff values resulting in optimal sensitivity (Se) to specificity (Sp) ratios were determined based on the ROC curves.
In the present study, the cut-off score for the optimal sensitivity and specificity to detect MCI appeared to be 21/22 for MoCA-BJ, at which the sensitivity and specificity were 68.7% and 63.9% respectively.
Due to the small number of patients included in our study, larger studies will be necessary to definitively establish a cut-off TIMP-1 level for optimal sensitivity and specificity to determine the probability for lack of response to CRT.
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