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The use of a more effective and advanced real-time scheduling technique, as the earliest deadline first (EDF), would allow for an optimal responsiveness of the system at possibly higher control rates.
We chose the period of growth factor stimulation to include at least part of the optimal windows of response to BMP4, Wnt3a and Activin A. Furthermore, based on our earlier results, we argued that the period of chimeric EB differentiation (d3 d5) fell outside the window of optimal responsiveness of the EBs to direct BMP4 or Wnt3a induction of Mixl1GFP+ cells.
Composite scores can be constructed utilizing cognitive items only, global or functional items only or a combination for optimal responsiveness.
These outcome measures have good reliability and validity [ 16, 17] within the populations for whom they were developed but may not have optimal responsiveness in MCI and pre-MCI since the outcomes were not developed specifically for the longitudinal monitoring of cognitive changes in a slowly progressive, mildly impaired population.
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Thus, multiple Rab proteins regulate the circulation of GLUT4 molecules within the endomembrane system, maintaining optimal insulin responsiveness within cells.
Altogether, our results suggested that IL-17A may be important for optimal protective immune responsiveness during pulmonary C. neoformans infection, but protective Th1-type immune responses are sufficient for protection against cryptococcal infection.
Recent advances in tissue culture systems acknowledge the importance of the tissue microenvironment in optimal functioning and responsiveness.
It is recommended for optimal sensitivity and responsiveness in clinical trials to use a combination of a generic and a disease-specific questionnaire [24].
These data suggest that TIEG1 functions upstream of Runx2 in the cascade of events that are initiated by TGFβ1 and BMP2 and implicate a role for TIEG1 in the optimal and immediate responsiveness of Runx2 to these cytokines in bone cells.
There is currently no agreement on the optimal approach to responsiveness analysis [ 15, 44- 48].
The computational analysis shows that a specific profile of subunit concentrations is crucial for optimal functioning and responsiveness of the system to input signals.
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