The reason for the maintenance of the three polymerase polypeptides may be chance or it is quite likely that the three PB1, PB2 and PA polypeptides act most efficiently as a set and so there may be pressure to maintain a gene constellation for optimal replication proficiency.
The number of clinical cases needed to meet optimal levels of proficiency in surgical procedures [ 2, 3], such as colonoscopy [ 4], has been evaluated often.
These findings suggest that limiting the physiologic levels of AID expression can be a regulatory mechanism that ensures an optimal balance between immune proficiency and genome integrity.
Our findings suggest that restraining the physiologic levels of AID expression can be a mechanism that allows the achievement of an optimal balance between immune proficiency and genome integrity.
Optimal training required for proficiency in bedside ultrasound is unknown.
Although its scope has been defined by the American College of Emergency Physicians, more research is needed to define an optimal F-TTE training program, including assessment of proficiency.
The researcher proposes an optimal performance model for addressing the issue of language proficiency level: (a) two primary dimensions; fluency and accuracy; and (b) two secondary dimensions; complexity and lexical variety.
Furthermore, because the main aim of this paper is to examine the possible implications of a rotated questionnaire design for the proficiency estimates rather than search for the optimal questionnaire rotation design, we elected to use the two-form design.
Because it does not simulate the reductions in air density, which affect motor ball trajectory and consequently motor skill proficiency, 103 using normobaric hypoxia is not optimal for preparation for competition at a natural altitude.
Unfortunately, monitoring and proficiency testing are currently suboptimal because they do not use optimal low-cobalamin control specimens.
Although well documented in the literature that proficiency based progression training has been qualitatively shown to the optimal approach to skill acquisition, due to time constraints it was no possible to analyse this within our cohort [ 26].
