Sentence examples for optimal lead from inspiring English sources

However, even in case of optimal lead placement, VV delay optimization can be of importance: some patients exhibit a significant delay between LV pacemaker stimulation and LV depolarization which can be counteracted by pre-exciting the LV pacing lead relative to the RV pacing lead (Fig.  5).

The goal of any hit-to-lead effort is the identification of an optimal lead series and its liabilities for transition to lead optimization efforts.

Accordingly, it is necessary to understand the effects of lead time on driving behaviors and explore the optimal lead time in various collision scenarios.

Among them, the optimal lead compound 17 exhibited a considerable agonistic activity (45.78%) compared to the NIH screened compound 1 (15.32%).

Thus, these coumarin derivatives merit investigation as novel potential antitumor agents with further structural modification to produce an optimal lead compound and elucidate the detailed pharmacological mechanism(s).

Selection of a sequence for further modifications to yield an optimal lead compound came down to a few key biophysical properties: low solution concentrations that yield channel activity, greater ensemble conductance, and enhanced ion selectivity.

Light intensities above optimal led to an irreversible inactivation of PSII (Tolstygina et al., 2009; Tsygankov et al., 2006).

However, increasing the cellular concentration beyond the optimal led to a sharp decrease in activity, probably due to increased cell concentration (proportional to enzyme concentration) and the maintenance of a constant concentration of an inhibitor of catecholase activity (ascorbic acid).

Of these, 40 (31%) were passive fixation right atrial (RA) or RV pacemaker leads, 33 (26%) were active fixation RA or RV pacing leads, 41 (31%) were single- or dual-coil defibrillator leads, and 15 (12%) were coronary sinus LV pacing leads, which were extracted due to sub-optimal function (phrenic nerve capture, or sub-optimal lead positioning).

In "Optimal release lead time of process 2", optimal release lead time of process 2 is developed, and in "Optimal release lead time of process 1", optimal release lead time of process 1 is discussed, and thus pairs of optimal base stock levels and optimal release lead time are derived for given demand lead time.

Through theoretical analysis, explicit expressions on optimal release lead time and optimal base stock levels are obtained for each demand lead time.