However, although children and carers perceived support groups as a source of HIV information, discussions suggested that the majority of children who attended support groups had sub-optimal knowledge of HIV.
More recent studies have been conducted to establish the optimal knowledge and skills of infection prevention specialists and of staff-to-bed ratios, but clear recommendations on effective organisation of staff have not yet emerged [ 41].
Graphical and descriptive information was developed and tested for ease of understanding and comprehensiveness of optimal knowledge transfer.
Graphical and descriptive information was developed and tested to establish ease of understanding and to ensure comprehensiveness of optimal knowledge transfer.
However, many challenges can be recognized immediately and need to be addressed properly, such as optimal knowledge databases to use, suitable formats of expert knowledge, reasonable ways to integrate these disparate kinds of data, and appropriate selection strategies.
Considering that huge increase, we can only observe that either the resource growth is done consistently thanks to effective annotation guidelines, or it is done in such a way that minor inconsistencies are compensated by the increase of evidences: the optimal knowledge base must just contain as many assignments as possible.
Our comparisons focus on simple feedback rules versus rules which are optimal, given knowledge of the correct economic structure and the appropriate loss function for the policymaker.
This is exacerbated by lack of awareness of Codes of Ethics and sub-optimal knowledge among nurses of what constitutes good ethical practice (19, 21, 31, 32).
However, the fact that a few regular support group attendees still had sub-optimal overall knowledge of HIV and on-going and unresolved questions about being cured and the duration of taking pills points to the inadequacy of relying solely on support groups to meet children's HIV and drug information needs.
When actors adhere to their scale preferences and these do not match well with the bio-geomorphologically based concepts, this can lead to conflicts amongst actors, sub-optimal use of the concepts and sub-optimal knowledge development on the functioning of an innovative concept in interaction with its social, physical and institutional context.
