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Finally, a Surrogate Based Optimization SBOO) is carried out and the Pareto optimal individuals according to the SBO are recomputed by CFD for final performance evaluation.
It is worth noting that duplicate individuals are deleted in the preservation of optimal individuals.
The rate of the Muller ratchet depends on the number of optimal individuals n o with fewest mutations.
In an endangered population, choosing optimal individuals for mating and designing an appropriate mating scheme can help to monitor the genetic variation and the average relatedness among individuals.
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We used the dose optimization software program BestDose to estimate each individual patient's pharmacokinetics and the optimal individual dosages for each patient.
In the ensuing 16-week maintenance phase, riociguat was continued at the optimal individual dose.
Then two SOC methods are applied to determine the optimal individual controlled variables (CVs) and measurement combinations as CVs.
It is suggested that these differences may be relevant to design optimal individual training programmes and methods.
Through the analysis, we derive a simple optimal individual-based reward system which depends on the amount and the productivity of shared knowledge.
Our algorithm corresponds to a variant of the population-based incremental learning (PBIL) genetic algorithm, with a specific "optimal individual" operator.
We suggest several approaches for designing the optimal individual sgRNA and an approach to compute the optimal set of sgRNAs for cases when the experimental platform allows for more than one.
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