We concluded that CD4-derived IL-2 is required for optimal help but that other IL-2 sources may also be involved.
During primary responses, naïve CD8+ T cells may need "CD4 help" for optimal development of memory populations.
They also excel in antigen crosspresentation to CD8+ T cells 21, 26, 27 and, therefore, can concomitantly present antigen to both CD4+ and CD8+ T lymphocytes, allowing optimal delivery of CD4+ T-cell help for CTL priming.
Former Google Executive to Build AOL's Future and Help Determine Optimal Structure for AOL.
Ultrasound ONS measurements may detect patients with neurological complications of preeclampsia, which can help identify optimal time for delivery by balancing fetal/neonatal risks and risks of adverse maternal neurological outcome.
With the wealth of data now available regarding the perioperative status of many of these patients, further research is needed to help facilitate optimal care for postsurgical patients.
Looking to these free-living models may help identify optimal conditions for generating lines of nematodes that stably express and inherit transgenes.
Studies such as these can be used to identify specific times marked by high-level alcohol use to help determine optimal times for intervention.
Assays that quantify toxin levels or antibody response could enable earlier diagnosis and treatment and help identify optimal timing for antitoxin administration.
