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For this mutant, the MD simulations suggest that the presence of F128 on β-strand 4 is important for maintaining optimal flexibility in active site loop 1.
To achieve optimal flexibility in the statistical adjustments, we used natural splines to allow for non-linear variations in age, period, and cohort effects (see R code in supplementary appendix d).
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We addressed this by giving special attention to the format of the treatment: we chose for an individual version in order to allow for optimal flexibility of patient inflow and to avoid waiting lists.
"The use of a virtual platform to explore the workings of the human brain provides optimal flexibility," Jeffrey Epstein remarked, who also supports MicroPsi's AI collaborators in Hong Kong, an open source AI foundation called OpenCog.
The SSGWEP invests heavily in transport and maintenance capabilities to ensure optimal flexibility.
In this approach, critical weighted values are automatically calculated over time based on observed scenes for optimal flexibility and parameterization.
The aim of the present work is thus to define design rules for optimal mechanical flexibility in a system that contains TSVs.
That there will generally be more than one non-dominated solution is a virtue because the availability of several "equally optimal" options allows flexibility in the ensuing decision-making process.
In addition, a Pareto-optimal set generated by multi-objective optimization can provide flexibility in selecting the most suitable watermarking parameters according to practical requirements.
The comparison of these observed values with 10,000 values from randomly generated networks suggests a relatively high flexibility in optimal complementarity sets for reserve selection.
However, several factors (reduction of cost, improved process efficiency, optimal use of equipment, flexibility in production capacity) are stimulating the pharmaceutical industry to investigate the opportunities offered by continuous processes.
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