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The main reason why we chose a two-tier clustering approach (data → coexpression network → clustering) is that it allows simulated annealing-based optimization of the clustering parameters to obtain optimal coverage of the coexpression network, in terms of module overlap and redundancy.
Use of this reference was intended to provide optimal coverage of the spotted genes.
This combination of gas flow, height, and deposition rate gave optimal coverage of the tissue sections.
Select a subset of the generated fragments, retaining optimal coverage of the targeted regions using the PieceMaker API.
(3) Most importantly, the surgeon can interrogate the operating bed with the hand-held probe from any desired angle, thereby providing optimal coverage of the tumor resection bed.
We preselected 272 loci from the map in Syed et al. (2006) for our analysis, aiming at an optimal coverage of the genome and the nine linkage groups.
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22 Hence, programming in STN-DBS could face the dilemma of needing some current spread into the internal capsule for optimal coverage of those pyramidal tract collaterals, while at the same time avoiding inadvertent stimulation of adjacent corticospinal and corticobulbar fibers.
A set of epitopes with optimal coverage of both the different Ebola strains and the HLA alleles prevalent in the populations of interest (US and West Africa) was selected as follows.
Alternatively, significant linkage may have been missed as a result of sub-optimal coverage of the genome by the STR marker set used, which may not have extracted all the inheritance information contained in the dataset.
We gave examples from rural and semi-urban settings in 5 different provinces that sub-optimal coverage of the HBV vaccine birth dose since its introduction in 2003 threatens the possibility of achieving this objective.
Information on the extent of MDR-TB from Africa region is very limited, probably due to poor laboratory facilities, poor surveillance mechanisms and reporting procedures, outdated databases and sub-optimal coverage of the infrequent surveys.
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CEO of Professional Science Editing for Scientists @ prosciediting.com