Sentence examples for optimal conjugation from inspiring English sources

The solution was gently stirred for 90 min at room temperature for optimal conjugation and finally centrifuged (1,000×g, 10 min) to remove large aggregates.

However, the availability of functional groups such as primary amines or free sulfhydryls in an immunoglobulin molecule is the limiting factor for optimal conjugation and, therefore, determines the sensitivity of an assay.

To identify optimal conjugation conditions, various amounts of whole virus (36 μg, 18 μg and 9 μg) were separately reacted with 350 μg of oxidised mannan, and the resulting preparations were analysed by gel electrophoresis.

Such a methodology would also allow the construction of a range of biologics with dual function, e.g. theranostics, or facilitate the optimal conjugation of both a drug, or imaging probe, with a lifetime extension technology.

However this approach requires basic aqueous conditions leading to competitive hydrolysis of the NHS ester, resulting in sub-optimal conjugation yields (<50%).

Our novel and practical chemoenzymatic bioconjugation platform enables exploring bioconjugate SAR space in order to find optimal combinations of conjugation site and linker chemistry to produce ADCs with enhanced stability, safety, and efficacy.

Lysine modification is sub-optimal as deleterious conjugation to lysine residues in the antigen binding region of the antibody can occur.

Another important component of the mentioned X-ray sensitizer is the way of keeping scintillating and sensitizing parts together at the distance optimal for EEET; chemical conjugation [2, 3], electrostatic attraction [8, 12], surfactant [11], or polymer shell [4] could be mentioned.

The symbiosis plasmid of strain HAMBI 1141 was shown to transfer by conjugation under optimal conditions.

A molar ration of 5 1 (dye chemokine) in the conjugation was found optimal to achieve nearly complete conversion to the SDF-1-IRDye800CW SDF-1-IRDye800CW SDF-1-IRDye800CW

The study also demonstrated that MorHap-BSA conjugates with a hapten density gradient could be synthesized in good yields using different molar-fold excess of the linker and optimal hapten:maleimide-BSA molar conjugation ratios.