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This is further reinforced by the finding from a study including a wide age range of elderly subjects that the relationship between blood pressure and cognition is not linear and the suggestion that there could be an optimal level of blood pressure that supports optimal cognitive function and that deviation from this increases the likelihood or risk of cognitive decline [ 44].
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This low number indicates sub-optimal cognitive function, and variable response to volitional muscle testing is not surprising.
So that optimal cognitive function is maintained and the progression of AD into the dementia phase is deferred, a diagnostic framework for predementia AD is needed.
These benefits include enhancement of existing cognitive function and maintenance of optimal cognitive function, as well as prevention or delayed progression of cognitive diseases, such as Alzheimer's dementia or other neurocognitive disorders.
On the other hand, physical activity leads to creative thinking, innovation, and optimal cognitive function.
Cognitive function was assessed with the mini-mental state examination (MMSE), with scores ranging from 0 to 30 (=optimal function) [ 16] and was stratified in four groups: MMSE score <19 points (severe cognitive impairment), 19 23 points (moderate cognitive impairment), 24 27 points (mild cognitive impairment) and 28 30 points (optimal cognitive function).
MMSE scores range from zero points (very severe cognitive impairment) to 30 points (optimal cognitive function).
3 Under normal homocysteine levels, where the blood brain barrier is intact, cholesterol levels are maintained to achieve optimal cognitive function.
The most important clinical implication is that multimorbidity can only be used as a predictor for disability in ADL in older people with optimal cognitive function.
Multimorbidity only predicted accelerated increase in disability in ADL in older people with an optimal cognitive function (MMSE score ≥28 points).
The Study of Osteoporotic Fractures has shown that lack of diabetes was predictive of maintaining optimal cognitive function over a 15-year follow-up as opposed to minor cognitive decline in older women (32).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com