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They either converge to a policy that may not be optimal against the specific opponents' policies, or they may not converge at all.
By local robustness, we refer to the calculation of control solutions that are optimal against the least favorable model among models close to an initial baseline.
The analysis model specifies what must be present for the solution to be correct; design specifies a solution that is optimal against the criticality-weighted set of design criteria.
This simply says that the repertoire of antibodies that was built upon infection with a given pathogen will not be optimal against an antigenically distinct pathogen.
It does not address the wider question of whether the 42 states are all appropriate or optimal against other criteria.
The transmission/disequilibrium test (TDT) [ 18] is a one-df test for association, which is optimal against the same alternative hypothesis as the one-df test for population-based studies, which was discussed in the first section of this review.
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The fingerprinting capacity, which can be computed information-theoretically, is an upper bound on the fingerprinting rate that can be achieved against colluders who employ an optimal strategy against the tracing scheme.
The main findings are: (i) Countercyclical reserve policies protect the optimal equilibrium against modest shocks but are powerless against large shocks.
Since the mucosa is often the primary sight of exposure, long-term, localized immune responses against Ebola virus are desirable for providing optimal protection against infection.
Conclusions about the robustness of an optimal design against misspecification of model parameters and choice of optimality criterion are drawn based upon our results.
Although CD4 T cells are crucial for defense against M.tb, it is still not clear whether the optimal response against M.tb in fact involves both CD4 and CD8 T cells.
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