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Future detailed optimization studies for developing the optimal administration protocol are required before clinical application of Smaducin-6 to sepsis.
An optimal administration protocol to induce a maximal effect of anesthetic preconditioning has not been evaluated to date.
Nevertheless, the application of our findings to humans will require the determination of the minimal effective dose in humans and of the optimal administration schema.
This paper addresses the problem of optimal administration of chemotherapeutic agents for the treatment of brain tumors by convection-enhanced drug delivery.
A series of experiments were designed to verify the optimal administration time and dose of T and to explore its potential protective mechanisms on spatial ability in Aβ + GDX rats in the Morris water maze test.
Thus, the optimal administration schedule is still unknown.
Similar(22)
The proposed approach is then used to design optimal chemotherapy administration for the cancer treatment.
Subjects received comprehensive training on appropriate device placement and adjustment of stimulation intensity for optimal dose administration.
Thus, optimal dosage, administration scheme, formulation remain to be assessed in this specific population of patients [54].
In this paper the model predictive control (MPC) technology is used for tackling the optimal drug administration problem.
Pharmacokinetics were melded with a viral dynamical model to design an optimal drug administration regimen such that the basic reproductive number for the virus was minimized.
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