Two relevant points arise from a comparison of Bayesian optimization with the grid search method (which sometimes outperformed Bayesian optimization): obtaining optimal accuracy with the grid search method required many more calculations, and even when grid search yielded higher accuracy values than Bayesian optimization, the difference between the two was approximately 1 2%.
A similar observation was made for the global and fingerprint-based analysis; Bayesian optimization provided the best average AUC and average optimal accuracy for all fingerprints, as well as the global average value of this parameter.
In those meta-analyses, accuracy data from non-standard cut-offs have been included when primary studies only report optimally accurate cut-offs, but do not report less optimal accuracy results from standard cut-offs.
Similarly, the average AUC and optimal accuracy values calculated for various targets were highest for Bayesian optimization in the great majority of cases.
The analysis of the results obtained for the example target/fingerprint pair 5-HT _textt {2A}), ExtFP; Table 3) shows that both the highest AUC and final optimal accuracy values were obtained with the Bayesian strategy for SVM optimization.
On the other hand, the group of targets for which the average optimal accuracy values were the highest for methods other than Bayesian optimization was a bit more extensive (i.e., M _text {1}), ERK2, A _text {1}), beta3AR, HIVi, IR).
It shows optimal accuracy at Courant numbers of 10 20, more than an order of magnitude higher than explicit methods.
Furthermore, the new experimental procedure almost achieves optimal accuracy with only 12-position which is half the cost of the widely adopted 24-position experimental procedure for achieving optimal accuracy.
We find that adapting the antenna setup to the particular situation is mandatory for an optimal accuracy.
Numerical results indicate that these two methods provide a similar optimal accuracy in solving both 2D Poisson's and parabolic equations.
The resulting scheme is able to stabilize the solution in the vicinity of discontinuities and retains the optimal accuracy for smooth solutions.
