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Still, since optical modalities are for the most part not approved for human use, researchers interested in clinical medicine must look elsewhere for molecular imaging.
Next to the development of multimodal tracers that combine two signatures, SPECT and optical modalities can also be combined on a single device with a single user interface.
The creation of the models, discussed here, highlight similarities that can be applied to create models from many microscopy techniques including electron microscopy and other optical modalities.
Even though the specific accumulation of our bimodal probe has to be further improved, it could be already used for cell imaging by MRI and optical modalities.
We have also compared the two optical modalities.
Snapshot spectral imaging devices will also play a vital role for emerging optical modalities that require spatial-spectral information.
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This surface-based phenomenon imparts a size- and shape-dependent optical modality to AuNPs and AgNPs, which can be exploited for bio-imaging, sensing and labelling [48].
By attaching Raman probes onto the surface of gold shell, the nanocomposites exhibit the potential to serve as surface-enhanced Raman scattering (SERS) active substrates for optical modality identification of cancer cell.
This can be accomplished with spectral imaging, which is an optical modality that collects a full set of spatial and spectral information called a "datacube".
An improved optical modality in terms of technology and image quality called SDF imaging has recently been developed for viewing the microcirculation in patients [ 4, 35].
Optical coherence tomography (OCT) has attracted much attention as a noninvasive optical modality in the realm of biomedical imaging because of its micrometer resolution and appreciable imaging depth, high speed, and high sensitivity [ 4– 8].
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