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One of the major shortcomings of this technique, as in all optical imaging methods, is the limited ability of light to penetrate deep into tissue.
Second, using sophisticated optical imaging methods, he studies abnormal embryonic heart function in different animal models of human disease, including Xenopus (tadpole) and Drosophila (fruit fly).
His research uses innovative optical imaging methods to better understand and treat pediatric disease, including congenital heart disease and ciliary disease.
PAT inherits the advantage of high optical contrast in optical imaging methods while breaking the optical diffusion limit on the penetration of high-resolution optical imaging by detecting ultrasound.
Most imaging modalities, including MRI, computed tomography, positron emission tomography, single photon emission computed tomography, ultrasound and a variety of optical imaging methods can be adapted to reveal insights into cellular function3.
It provides greater penetration depths than purely optical imaging methods that rely on ballistic photons, such as light microscopy and optical coherence tomography (OCT), and yields higher resolution than diffuse optical methods.
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Optical coherence tomography (OCT) is an optical imaging method that produces high-resolution cross-sectional images of the esophagus.
Sutton, E. J. et al. An optical imaging method to monitor stem cell migration in a model of immune-mediated arthritis.
Decrease in embryo heart performance as ascertained using a novel optical imaging method developed in our lab.
The first one is the simultaneous observation of the phenomena by the micro-wave detection and the optical imaging method.
To address this, Dr. Hillman and her team employed a wide-field, optical imaging method that allowed them to visualize both changes in blood flow and neural activity simultaneously across the surface of the mouse brain.
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