However, they are known to encounter difficulties in finding variables "negatively" (oppositely) associated with each other [ 10].
Interestingly, as with ChREBP in this study, TRIB3 in its protein and mRNA forms are oppositely associated with breast cancer prognosis.
However, there are reports, including a prospectively conducted phase III clinical trial, of RRM1 either not being significantly associated or possibly oppositely associated with survival in lung cancer patients receiving a gemcitabine-containing regimen [ 10- 13].
Oppositely, 17 transcripts associated to muscle contraction were down-regulated such as components of the Z-disk (actn2, actn3), myosin heavy chain (myh2, myh3, myh4, myh7, myh10), myosin binding (mybpc1, mybpc3), tropomyosin (tpm1), troponin (tnnt2, tnnt3, tnni1, tnnc1), actin chain (acta1), and myosin light chain (myl3, myl4).
The predominant form of an ionized compound in octanol is an ion pair in which the oppositely charged ions remain closely associated.
Oppositely, appropriate empiric antimicrobial therapy was associated with a significantly lower A. baumannii-associated mortality (p = 0.03).
A CGI located within intron 10 of KCNQ1 and associated with an oppositely-oriented RNA transcript is involved in imprinting (paternal repression) of its locus [ 22].
Oppositely, an earlier age at menarche was associated with higher odds of being overweight at the age of 13. 22 Based on these results we could suppose that girls with a later age at menarche are less likely to be overweight at the age of 13 because the weight gain related with puberty occurs later; for this group the increase in BMI and BF% seems to happen between the age of 13 and 17 years.
This might occur by both positive and negative feedback between oppositely oriented complexes, and requires the peripheral membrane associated PCP components.
Note that, in ionic polymerization, an oppositely charged ion (in this case, bisulfate ion [HSO4−]) is associated with the chain end to preserve electrical neutrality.
Notably, HLA-DR molecules not associated with RA (e.g. DRB1*0402) contain oppositely charged amino acids at some of these positions (DERAA).
