Exact(4)
Therapeutic targeting of TH2 or TH17 cytokines can thus amplify activity of the opposing pathway.
Studies with extended exposure to agonists in airways and bladder have reported both sensitization and attenuation of the opposing pathway.
Taken together, these data show that chronic activation of one pathway may have effects on the opposing pathway, but the direction of such cross-regulation may differ among experimental models and also from the interaction seen upon acute agonist administration.
It is possible that cdc-42 and pat-3 could be acting in parallel pathways that indirectly oppose the activities of mir-34 and mir-83, such that the observed suppression is the result of decreasing the activity of an opposing pathway.
Similar(56)
However, the distinction between them is a question of the probabilities of going via these two opposing pathways.
In-depth investigation of these patterns identified potential regulatory proteins involved in balancing these opposing pathways.
Our findings indicate the activity of opposing pathways in INRs, in which stromal cell production of both IL-7 and IL-7Rα seems to be elevated.
The processes regulating these two opposing pathways have not been thoroughly elucidated to date.
The inhibition of 11β-HSD1 activity or activation of opposing pathways could have beneficial effects in vivo.
It is plausible that riboswitches could provide one means of integrating such opposing pathways.
One simple explanation would be LY30 triggers two opposing pathways that regulate cFLIP in opposite ways.
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