Sentence examples for opposing inflammatory from inspiring English sources

Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

The results provide evidence of negative feedback regulation opposing inflammatory cytokines that have self-sustaining activities and suggest a cytokine-driven oscillator circuit may drive the periodic disease activity observed in many SLE patients.

It also highlights the potential problems with globally inhibiting kinase families whose members exhibit opposing inflammatory properties, such as JAK1 and JAK3.

The exception was suppressor of cytokine signalling 3 (SOC3) which was 7 fold increased in expression (Figure 3 and supplemental data set S4) and this would be consistent with attempts to suppress the deleterious impact of MOF induced cytokine signalling [42] on insulin action as SOC3 can oppose inflammatory IL6 signalling.

IL-27 produced by human macrophages during MTB infection opposes inflammatory responses [ 17, 19- 21].

Despite our views [ 38], authors still propose a two-wave concept with SIRS appearing before CARS, although they admit that 'rigorous examination of previous studies provides evidence that both pro-inflammatory and opposing anti-inflammatory response(s) occur concomitantly in sepsis' [ 1].

We compared genome-wide features of regulatory elements and their activity in two closely related cell lineages, Treg cells, and effector CD4+ T cells, which represent alternative cell fate choices during T-cell differentiation and fulfill opposing anti-inflammatory and pro-inflammatory immune functions.

DUSP1 opposes the inflammatory response by blocking crucial signaling pathways.

In healthy individuals, negative feedback regulation may be required to oppose the inflammatory state and restore homeostasis, but in SLE, regulation may be deficient and a chronic state of aberrant immune activation may result.

The function of Mer has been recently refined as a tolerogenic receptor specialized for the clearance of apoptotic cells in homeostatic as opposed to inflammatory environments.

The objective was to evaluate the changes in S100A8 S100A9, and their complex (S100A8/S100A9) in cartilage during the onset of osteoarthritis (OA) as opposed to inflammatory arthritis.