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The migration is driven by two abiotic gradients: a seasonal rainfall gradient that increases from the Serengeti plains in the southeastern portion of the ecosystem towards the northwestern woodlands near Lake Victoria, and an opposing gradient of increasing soil fertility.
Analysis of actin bundle anisotropy shows that actin bundling forms an opposing gradient, with the most organized actin bundles towards the bleb tip.
Through interaction of bicoid with a region within the 3' UTR of caudal mRNA, the translation of caudal mRNA is inhibited resulting in an opposing gradient of caudal expression.
This gradient is believed to offset the opposing gradient in sarcomere extension during filling, thus leading to a more uniform transmural distribution of SL at end diastole and hence more uniform development of systolic force.
GFP MEG-3 forms an anterior-low/posterior-hiGFP MEG-3nt along the length oforms zygote, and the RNanterior-low/posterior-highich is required for full disassembly, forms an opposingradientnt with higher levels in the alongior (Schuberthet alength00).
How the complementary expression patterns of Fj and Ds result in the accumulation of Ft and Ds on opposing cell edges is still under investigation, however, the data suggest that higher proximal expression of Ds and the opposing gradient of Fj expression leads to a gradient of Ft Ds dimer formation (Casal et al., 2006; Lawrence et al., 2008; Strutt, 2009).
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Opposing gradients of bone morphogenetic protein and Nodal can induce the formation of a zebrafish embryo.
Possibly, the low predictability for the field in Silstrup originated from opposing gradients in clay and oxalate-extractable Fe across the field.
The expression patterns of Ephs and ephrins in opposing gradients both in the retina and the tectum/colliculus, label the local addresses on the target and give specific sensitivities to growth cones according to their topographic origin in the retina.
The lodgment of HSC within the subendosteal region is probably determined by opposing gradients of factors associated with osteoblasts, such as calcium ions [3], [58], and those produced by BMSC, such as CXCL12.
On the other hand opposing gradients are unlikely in vivo, but MSC plasticity has been previously demonstrated using stiffness and growth factor cues of opposing lineages: MSCs on 1 kPa hydrogels challenged with either muscle or osteo-inductive media displayed a mixed phenotype after 1 week but were unaffected by the inductive media after 3 weeks [11].
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