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All techniques present opportunities for further optimisation of outputs, and hence for greater cumulative public value.
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These new heterocyclic scaffolds constitute valuable starting points for further optimisation and give the opportunity to explore new, tractable, chemistry routes.
Considerable differences remain between hospitals for the most frequently used CT protocols, indicating the need for further optimisation.
This research provides proof of concept for further optimisation of organo-mineral fertiliser manufacture using readily available lignite resources.
This study identifies key parameters associated with the Quickstep process, providing a basis for further optimisation.
The good qualitative agreements achieved are useful for further optimisation of product design.
Since the validation mixtures depicted in Table 2 were obtained by means of the numerical optimisation function of Design-Expert®, these mixtures can also be used for further optimisation studies.
This indicated the need for further optimisation.
This provides potential for further optimisation.
For further optimisation one of the antisera (CF141) was affinity purified using a protein A column.
The thiazolidinone series, in particular compound 13, presents a good starting point for further optimisation.
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